This study examines the impact that fermenting with whole clusters or with stem inclusion has on Chambourcin wines. Chambourcin grapes were harvested from the same block on the same day and separated into 3 T Bins. One T Bin received 100% destemmed and crushed fruit (control). The second T Bin received 30% whole clusters at the bottom, and then was filled with 70% destemmed and crushed fruit (by weight). The third T Bin received 30% of the stems by weight from the control at the bottom of the T bin, and then were filled with the same weight of destemmed and crushed grapes as the control and treatment. All other treatments between musts and wines were identical. pH was slightly increased by whole cluster and stem inclusion, and TA and tartaric acid was slightly decreased. Pyrazine was slightly increased by the treatments. Color intensity was not much affected by the treatments. Catechin, epicatechin, and quercetin were slightly increased by the treatments. Tannin was increased by the treatments, and anthocyanins were decreased by the treatments. Overall, stem inclusion seemed to result in lower Bitterness, and may have lowered Astringency and Herbaceous/Green character. The whole cluster and the control treatments tended to be higher in Herbaceous/Green character. The intensity for the descriptors for whole cluster inclusion seemed to change over time, perhaps due to ester qualities decreasing over time in bottle. Preference trends were hard to determine, although whole cluster and stem inclusion wines tended to be more preferred over the control.